McMaster
Tuesday, February 09, 2010

Worth Mentioning

Participants needed for asthma study involving omega-3 fatty acid

Posted on August 01, 2008 at 04:30 PM.

We need your help in a clinical research study assessing the role of dietary omega-3 fatty acid supplementation from fish oils in people with asthma.

Omega-3 fatty acids and their role in health and disease have been studied extensively, with the observation that they may have some therapeutic benefits in inflammatory disease.

There is epidemiological evidence that suggests a diet rich in omega-3 fatty acids, predominantly from communities that eat fish regularly, have a protective effect on diseases with an inflammatory component such as cardiovascular disease and asthma. However, there is little direct evidence to support this observation in persons with asthma.

The western diet is currently rich in fats, however there is mounting evidence of a significant decrease in the content of omega-3s in the modern diet, which are essential and required in the diet. Supplementing the diet with omega-3 fatty acids may have therapeutic benefits, however this requires further research.

We are interested in assessing the effect of omega-3 fatty acids have on asthma by incorporating the latest diagnostic procedures as they may provide a more useful way to assess potential protective effects of such dietary changes in persons with asthma.

To be eligible to participate, you must be:

  • male or female

  • 18 to 55 years of age

  • non-smoker

  • taking asthma medications and requiring bronchodilator medication for periodic symptom relief and/or to protect against exercise-induced asthma symptoms
  • Eligible participants will undergo:

  • comprehensive assessment of asthma and assessment of the effects of your current therapy

  • blood samples are required for cholesterol testing

  • provided with dietary supplementation of omega-3 fatty acid capsules for two three-week periods

  • requires four two-hour visits to the Firestone Institute for Respiratory Health research clinic in Hamilton over a nine-week period.
  • Participants will receive remuneration for their time and participation.

    For more information, please contact John Brannan at 905-522-1155, ext. 33584 or e-mail brannan@mcmaster.ca.


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